1. Preheat your oven to 375°F (190°C).

2. In a large skillet, cook the ground beef over medium heat, stirring occasionally to break it apart.

3. Cook the beef until it is fully browned, about 6-8 minutes.

4. Drain any excess grease from the skillet and return the beef to the heat.

5. Stir in the garlic powder, onion powder, and black pepper, and cook for another 1-2 minutes until the spices are well combined with the beef.

6. Remove the skillet from the heat and allow the beef mixture to cool slightly.

7. In a mixing bowl, combine the cream cheese, shredded cheddar cheese, and grated Parmesan cheese.

8. Add the cooled beef mixture to the cheese mixture and stir until everything is evenly mixed.

9. Open the can of refrigerated biscuit dough and separate the biscuits.

10. Flatten each biscuit into a small round disc with your hands or a rolling pin.

11. Spoon a generous amount of the beef and cheese mixture into the center of each biscuit.

12. Carefully fold the edges of each biscuit around the filling and pinch them together to form a sealed ball.

13. Place each filled biscuit bomb onto a baking sheet lined with parchment paper or a silicone baking mat, making sure they are evenly spaced.

14. Brush the tops of the biscuit bombs with the melted butter for a golden, crispy finish.

15. Bake the biscuit bombs in the preheated oven for 12-15 minutes or until the biscuits are golden brown and cooked through.

16. Remove the biscuit bombs from the oven and allow them to cool for a few minutes before serving.